Room Z06 FCBS

Analysis, Comparison and Classification of Protein Structures

Room CE1

Genome browsers with special emphasis in the ENSEMBL system

Room Z05 FCBS

Protein resources and tools: sequence, architecture and protein interactions

Room CC1D

Algorithms and tools for transcriptomics and multiple gene profiling using the open source platforms R and Bioconductor

Room Z06 FCBS

Analysis, Comparison and Classification of Protein Structures

Room CE1

Genome browsers with special emphasis in the ENSEMBL system

Room Z05 FCBS

Protein resources and tools: sequence, architecture and protein interactions

Room CC1D

Algorithms and tools for transcriptomics and multiple gene profiling using the open source platforms R and Bioconductor

Room CC1D

Immunoinformatics

Room Z06 FCBS

Next generation sequencing: an introduction for bioinformaticians

Room CE1

Functional Genomics

Room Z05 FCBS

Computer-Based Drug Design

Room CC1D

Immunoinformatics

Room Z06 FCBS

Next generation sequencing: an introduction for bioinformaticians

Room CE1

Functional Genomics

Room Z05 FCBS

Computer-Based Drug Design

SESSION I. Comparative Genomics and Evolution.

Chair of Session: Cristina Marino (Instituto Leloir, Argentina)

Location: Auditorium Juan Francisco Fresno (ground floor)

MM1 » The PhyloFacts-SchistoDB Schistosoma Database

Presenting Author: Kimmen Sjolander (University of California Berkeley)

Co-authors: Yaoqing Shen (University of California Berkeley, QB3); Ajithkumar Warrier (University of California Berkeley, QB3); Laila Nahum (FIOCRUZ Minas, Genomics and Computational Biology Group); Guilherme Oliveira (FIOCRUZ Minas, Genomics and Computational Biology Group)

MM2 » Identification of transcription regulation associated proteins in plants and stramenopiles

Presenting Author: Diego Mauricio Riaño Pachón (Universidad de los Andes)

Co-authors: Francisco J. Buitrago-Florez (Universidad de los Andes, Biological Sciences); Silvia Restrepo-Restrepo (Universidad de los Andes, Biological Sciences); Bernd Mueller-Roeber (Universität Potsdam, Institute of Biochemistry and Biology)

MM3 » Molecular Phylodynamics and Protein Modeling of Infectious Salmon Anemia Virus (ISAV)

Presenting Author: Eduardo Castro Nallar (Brigham Young University)

Co-authors: Marcelo Cortez-San Martín (Universidad de Santiago de Chile, Facultad de Química y Biología); Carolina Mascayano (Universidad de Santiago de Chile, Facultad de Química y Biología); Cristian Molina (Universidad de Santiago de Chile, Facultad de Química y Biología); Keith Crandall (Brigham Young University, Biology)

MM4 » Evolutionary events involved in pathogenic trait acquisition in Ascomycetes

Presenting Author: Aminael Sanchez-Rodriguez (Katholieke Universiteit Leuven)

Co-authors: Riet De Smet (Ghent University, Plant Systems Biology); Kristof Engelen (Katholieke Universiteit Leuven, Molecular and Microbial Systems); Qiang Fu (Katholieke Universiteit Leuven, Molecular and Microbial Systems); Yan Wu (Katholieke Universiteit Leuven, Molecular and Microbial Systems); Kathleen Marchal (Katholieke Universiteit Leuven, Molecular and Microbial Systems)

MM5 » Novel Classes of Eukaryotic Aspartic Proteases and the Identification of their Specificity Determining Residues

Presenting Author: María Revuelta (Universidad Nacional de Mar del Plata)

MM6 » Conformational diversity: Relationship with protein evolution and designability

Presenting Author: Diego Zea (Universidad Nacional de Quilmes)

Co-authors: Gustavo Parisi (Universidad Nacional de Quilmes, Centro de Estudios e Investigaciones); Cristina Marino Buslje (Fundación Instituto Leloir, Bioinformatics Unit)

Business Presentation with free Lunch Sponsored by Life Technologies (open to any interested people)

Location: Sala Colorada (ground floor)

SESSION II. Genomics, Proteomics, Metagenomics and Metabolomics.

Chair of Session: David Holmes (Fundación Ciencia & Vida; Universidad Andrés Bello, Chile)

Location: Auditorium Juan Francisco Fresno (ground floor)

MA1 » The ISA Commons – Towards interoperable data in bioscience

Presenting Author: Susanna-Assunta Sansone (University of Oxford)

Co-authors: Philippe Rocca-Serra (University of Oxford, Oxford e-Research Centre); Eamonn Maguire (University of Oxford, Oxford e-Research Centre)

MA2 » A Fast de novo Genome-Wide Tandem Repeat Discovery Algorithm

Presenting Author: Marcelo Gonçalves Narciso (Embrapa)

Co-authors: Michel Yamagishi (Embrapa); Marcelo Gonçalves Narciso (Embrapa, Bioinformatics)

MA3 » GOBOOT: testing set enrichment analysis robustness to background selection

Presenting Author: Cristobal Fresno Rodríguez (Catholic University of Córdoba)

Co-authors: Andrea Llera (Leloir Institute, CONICET, Laboratory of Molecular and Cellular Therapy); María R Girotti (Leloir Institute, CONICET, Laboratory of Molecular and Cellular Therapy); María P Valacco (Leloir Institute, CONICET, Laboratory of Molecular and Cellular Therapy); Juan A López (National Center for Cardiovascular Research, Madrid); Osvaldo L Podhajcer (Leloir Institute, CONICET, Laboratory of Molecular and Cellular Therapy); Mónica G Balzarini (National University of Córdoba, Biometry Laboratory); Federico Prada (UADE, Institute of Technology, School of Engineering and Sciences); Elmer A Fernández (Catholic University of Córdoba, CONICET, BioScience Data Mining Group)

MA4 » Computational Pattern Recognition for the Identification of Transposases in Prokaryotic Genomes: Challenges and Advances

Presenting Author: Gonzalo Riadi (Universidad de Talca)

Co-authors: David Holmes (Fundación Ciencia & Vida and Universidad Andrés Bello, Facultad Ciencias Biológicas); Gonzalo Riadi (Center of Bioinformatics and Molecular Simulation and Universidad de Talca, Engineering School)

MA5 » Spinal Cord Regeneration in Xenopus: A Transcriptomics Analysis

Presenting Author: Dasfne Lee-Liu (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas)

Co-authors: Juan Larrain (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas) Leonardo Almonacid (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas); Mauricio Moreno (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas); Rosana Muñoz (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas); Marcia Gaete (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas); Francisco Melo (Pontificia Universidad Católica de Chile, Facultad de Ciencias Biológicas)

MA6 » High-resolution community genomics of a hypersaline microbial ecosytem

Presenting Author: Juan Ugalde (University of California, San Diego)

Co-authors: Sheilla Podell (University of California, San Diego, Scripps Institution of Oceanography); Karla Heidelberg (University of Southern California, Department of Biological Sciences); Jill Banfield (University of California, Berkeley, Department of Earth and Planetary Sciences); Eric Allen (University of California, San Diego, Scripps Institution of Oceanography)

Poster Session I (Odd numbers)

Location: Central Square (ground floor)

Meeting of SoIBio and FreeBIT/CYTED: Societies and Networks promoting Bioinformatics for Life Sciences and Biomedicine in IberoAmerica.

Location: Sala Colorada (ground floor)

SESSION III. Macromolecule Structure/Function Prediction.

Chair of Session: Diego Ferreiro (Universidad de Buenos Aires, Argentina)

Location: Auditorium Juan Francisco Fresno (ground floor)

TM1 » Modeling proteins using supersecondary structure library and NMR chemical shifts

Presenting Author: Andras Fiser (Albert Einstein College of Medicine)

Co-authors: Vilas Menon (Albert Einstein College of Medicine, Systems and Computational Biology); Joseph Dybas (Albert Einstein College of Medicine, Systems and Computational Biology)

TM2 » Using correlation data and network decomposition to obtain sub-class determinants in protein families

Presenting Author: Lucas Bleicher (Universidade Federal de Minas Gerais)

Co-authors: Richard Garratt (Universidade de Sao Paulo, Instituto de Fisica de Sao Carlos); Ney Lemke (Universidade Estadual de Sao Paulo, Departamento de Fisica e Biofisica, Botucatu)

TM3 » Evolution of linear motifs within the intrinsically disordered and globular domains of the papillomavirus E7 oncoprotein

Presenting Author: Lucia Chemes (Fundación Instituto Leloir IIBBA-CONICET)

Co-authors: Juliana Glavina (Protein Physiology Laboratory, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina, Departamento de Química Biológica); Julian Faivovich (División Herpetología, Museo Argentino de Ciencias Naturales-CONICET, Buenos Aires, Argentina, Museo Argentino de Ciencias Naturales); Leonardo Alonso (Fundacion Instituto Leloir , Buenos Aires Argentina, IIBBA-CONICET); Cristina Marino-Buslje (Fundacion Instituto Leloir, IIBBA CONICET, Buenos Aires Argentina, Structural Bioinformatics Laboratory); Gonzalo de Prat Gay (Fundacion Instituto Leloir IIBBA CONICET, Buenos AIres Argentina, Protein Structure-Function and Engineering Laboratory); Sanchez Ignacio (Protein Physiology Laboratory, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina, Departamento de Quimica Biologica)

TM4 » Cross talk between DNA and Transcription factors

Presenting Author: Matias Machado (Institut Pasteur de Montevideo)

Co-authors: Pablo Dans (Institut Pasteur de Montevideo, Biomolecular Simulation Group); Sergio Pantano (Institut Pasteur de Montevideo, Biomolecular Simulation Group)

TM5 » Standardized comparison of structural alignments of catalytic domains in DNA polymerases from different methods

Presenting Author: Alex Slater (Molecular Bioinformatics Laboratory, Millennium Institute on Immunology and Immunotherapy. Pontificia Universidad Católica de Chile)

Co-authors: Manfred Sippl (University of Salzburg); Francisco Melo (Pontificia Universidad Católica de Chile, Depto. Genética Molecular y Microbiología)

TM6 » A Multidisciplinary Strategy for Function Assignment: The Enzyme Function Initiative from a Bioinformatics Perspective

Presenting Author: Daniel Almonacid (University of California)

Co-authors: Shoshana Brown (University of California San Francisco, Bioengineering and Therapeutic Sciences); Patricia Babbitt (University of California San Francisco, Bioengineering and Therapeutic Sciences)

Business Presentation with free Lunch Sponsored by Roche (open to any interested people)

Location: Sala Colorada (ground floor)

SESSION IV. Computer Aided Drug Design and Docking/Molecular Dynamics Simulations.

Chair of Session: Tomás Pérez-Acle (Universidad de Chile, Chile)

Location: Auditorium Juan Francisco Fresno (ground floor)

TA1 » Confidence Assessment of Candidate Drug Property Predictions by Subspace Mapping Methods

Presenting Author: Axel Soto (Universidad Nacional del Sur)

Co-authors: Ignacio Ponzoni (Universidad Nacional del Sur) Gustavo Vazquez (Universidad Nacional del Sur, Laboratory of Research and Development in Scientific Computing (LIDeCC)); Marc Strickert (Siegen University, Institute for Vision and Graphics); Ignacio Ponzoni (Universidad Nacional del Sur, Laboratory of Research and Development in Scientific Computing (LIDeCC))

TA2 » Docking Studies of a New Series of Analgesic and Anti-inflammatory Compounds (NSAIDs) with Cyclooxygenase

Presenting Author: Lucas Saraiva (Federal University of Minas Gerais)

Co-authors: Ihosvany Camps (Federal University of Alfenas, Department of Exact Science); Raquel Melo-Minardi (Federal University of Minas Gerais, Department of Computer Science ); Marcia Veloso (Federal University of Alfenas, Faculty of Pharmaceutical Science); Rodrigo Sailva (Federal University of São Carlos, Department of Chemistry)

TA3 » Desintegrin-like domains in computer aided drug design of integrin-specific inhibitors

Presenting Author: Jorge H. Fernandez (State University of North Fluminense)

Co-authors: Jorge Fernandez (State University of North Fluminense) Monika A. Coronado (UNESP-RP, Depto. de Física); Ana T.R. Vasconcelos (LNCC, BioInfo); Monica Lopes-Ferreira (Butantan Institute, LETA); Wilson Savino (Oswaldo Cruz Institute, Laboratory of Thymus Research)

TA4 » Using Computer Simulations to Understand Enzyme Mechanism: Application to Mycobacterium tuberculosis CYP121 Unusual Reaction

Presenting Author: Victoria Dumas (University of Buenos Aires)

Co-authors: Adrián Turjanski (University of Buenos Aires, Química Inorganica); Lucas Defelipe (University of Buenos Aires, Química Biologica); Marcelo Martí (University of Buenos Aires, Química Inorgánica)

TA5 » Topological constraints and challenges imposed by knots in proteins

Presenting Author: César Ramírez (University of Chile)

Co-authors: Jeffrey K. Noel (University of California San Diego, Center for Theoretical Biological Physics); Mauricio Baez (University of Chile, Department of Biology)

TA6 » Combined structure- and ligand-based virtual screening in the search of novel 11beta-hydroxysteroid dehydrogenase inhibitors for the treatment of metabolic syndrome

Presenting Author: Carlos Lagos (Pontificia Universidad Católica de Chile)

Co-authors: Andrea Vecchiola (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Fidel Allende (P. Universidad Catolica de Chile, Clinical Laboratory); Carolina Valdivia (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Cristobal A. Fuentes (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Sandra Solari (P. Universidad Catolica de Chile, Clinical Laboratory); Carmen Campino (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Rene Baudrand (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Cristian A. Carvajal (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Carlos E. Fardella (P. Universidad Catolica de Chile, Molecular Endocrinology Laboratory); Mariana Cifuentes (Universidad de Chile, Institute of Nutrition and Food Technology (INTA))

Poster Session II (Even numbers)

Location: Central Square (ground floor)

SESSION V. Biomedicine and Immunoinformatics.

Chair of Session: Alexis Kalergis (Pontificia Universidad Católica de Chile)

Location: Auditorium Juan Francisco Fresno (ground floor)

WM1 » MHCcluster, and method for functional clustering of MHC molecules

Presenting Author: Morten Nielsen (Center for Biological Sequence Analysis, BioCentrum, DTU)

Co-authors: Ole Lund (Center for Biological Sequence Analysis, BioCentrum, DTU, Department of Systems biology); Claus Lundegaard (Center for Biological Sequence Analysis, BioCentrum, DTU, Department of Systems biology)

WM2 » A step towards pan-specific prediction methods for MHC class II molecules: a projection of HLA-DR on to HLA-DP and HLA-DQ

Presenting Author: Edita Karosiene (Technical University of Denmark)

Co-authors: Morten Nielsen (Technical University of Denmark, Department of Systems Biology)

WM3 » Systematic prediction of ligand-receptor pair across the immunoglobulin superfamily using a novel sequence homology measure

Presenting Author: Eng Hui Yap (Albert Einstein College of Medicine)

Co-authors: Andras Fiser (Albert Einstein College of Medicine, Systems and Computational Biology); Tyler Rosche (Albert Einstein College of Medicine, Systems and Computational Biology)

WM4 » Common features in damaged DNA detection

Presenting Author: Juan José Cifuentes (Pontificia Universidad Católica de Chile)

Co-authors: Francisco Melo (Molecular Bioinformatics Laboratory, Depto. Genética Molecular y Microbiología. Pontificia Universidad Católica de Chile)

WM5 » A bioinformatics strategy for the design of diagnostic epitope discovery tools: first generation peptide microarrays for Chagas Disease

Presenting Author: Santiago Carmona (Universidad Nacional de San Martín)

Co-authors: Fernán Agüero (Universidad Nacional de San Martín) Paula Sartor (UBA, Dept. of Microbiology-Fac.Med.); Maria Susana Leguizamón (UBA, Dept. of Microbiology-Fac.Med.); Oscar Campetella (UNSAM, IIB); Fernán Agüero (UNSAM, IIB)

WM6 » Annotation of putative AraC/XylS-family transcription factors of known structure but unknown function

Presenting Author: Andreas Schüller (Pontificia Universidad Católica de Chile)

Co-authors: Alex W. Slater (Pontificia Universidad Católica de Chile, Depto. Genética Molecular y Microbiología); Tomás Norambuena (Pontificia Universidad Católica de Chile, Depto. Genética Molecular y Microbiología); Juan José Cifuentes (Pontificia Universidad Católica de Chile, Depto. Genética Molecular y Microbiología); Francisco Melo (Pontificia Universidad Católica de Chile, Depto. Genética Molecular y Microbiología)

The ISCB Open Member Meeting (open to any interested people)

Location: Sala Colorada (ground floor)

SESSION VI. Functional Genomics and Systems Biology.

Chair of Session: Rodrigo Gutiérrez (Pontificia Universidad Católica de Chile)

Location: Auditorium Juan Francisco Fresno (ground floor)

WA1 » Evolution of domain architectures and catalytic functions of enzymes in metabolic systems

Presenting Author: Chen-Hsiang Yeang (Academia Sinica)

Co-authors: Summit Suen (Academia Sinica, Institute of Statistical Science); Henry Horng-Shing Lu (National Chiao-Tung University, Institute of Statistics)

WA2 » Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection

Presenting Author: Kathleen Marchal (Ghent University)

Co-authors: Hong Sun (K.U.Leuven, Microbial and Molecular Systems); Tias Guns (K.U.Leuven, Computer Science); Ana Carolina Fierro (K.U.Leuven, Computer Science); Lieven Thorrez (K.U.Leuven, Interdepartmental Stem Cell Institute); Siegfried Nijssen (K.U.Leuven, Computer science)

WA3 » LitProf – Gene Classifier: A text-mining gene function predictor for prokaryotes

Presenting Author: Roney Coimbra (FIOCRUZ-Minas)

Co-authors: Raul Torrieri (FIOCRUZ-Minas, Center for Excellence in Bioinformatics); Francislon Oliveira (FIOCRUZ-Minas, Center for Excellence in Bioinformatics); Guilherme Oliveira (FIOCRUZ-Minas, Center for Excellence in Bioinformatics)

WA4 » Discriminative local subspaces in gene expression data for effective gene function prediction

Presenting Author: Tomás Puelma (Pontificia Universidad Católica de Chile)

Co-authors: Rodrigo Gutiérrez (Pontificia Universidad Católica de Chile); Alvaro Soto (Pontificia Universidad Católica de Chile, Computer Science); Rodrigo Gutierrez (Pontificia Universidad Católica de Chile, Molecular Genetics and Microbiology)

WA5 » The just-in-time expression of yeast ribosomal proteins

Presenting Author: Andrzej Kudlicki (University of Texas Medical Branch)

Co-authors: Xueling Li (University of Texas Medical Branch, Institute of Translational Science); Gang Chen (Central South University, Computer Science)

WA6 » Deciphering human protein interactome using structural complexes

Presenting Author: Anna Panchenko (National Institutes of Health)

Co-authors: Manoj Tyagi (National Institutes of Health, NCBI); Kosuke Hashimoto (RIKEN, RIKEN); Benjamin Shoemaker (NIH, NCBI); Stefan Wuchty (NIH, NCBI)

Conference Banquet

Location: Castillo Hidalgo, Cerro Santa Lucía, Santiago [SEE MAP HERE]

SESSION VII. WorkShops on Next Generation Sequencing Technologies and GRID Computing.

Chair of Session: Romilio Espejo (Omics Solutions, Chile)

Location: Auditorium Aula Magna Eleodoro Matte Ossa (second floor)

SESSION VIII. Round Tables on Bioinformatics Research, Training and Education in Iberoamerica.

Chair of Session: Danilo González (Universidad Andrés Bello, Chile)

Location: Auditorium Aula Magna Eleodoro Matte Ossa (second floor)